Irreversible Electroporation in Clinical Practice

Irreversible Electroporation in Clinical Practice

Meijerink, Martijn; Scheffer, Hester; Narayanan, Govindarajan

Springer International Publishing AG

08/2017

285

Dura

Inglês

9783319551128

15 a 20 dias

This book provides a comprehensive overview of the clinical use of irreversible electroporation (IRE) - better known by its commercial name, NanoKnife - which is one of the most exciting new needle-guided cancer treatments.
Introduction: History of image-guided tumor ablation.- History of electroporation. Preclinical Research: Multi-scale biophysical principles in clinical irreversible electroporation.- Numerical modelling for prediction and evaluation of treatment outcome.- The effect of irreversible electroporation on blood vessels, bile ducts, urinary tract, intestines and nerves. Technique, tips and tricks: Anaesthetic management during irreversible electroporation procedure.- Complications and procedures to enhance safety.- Treatment planning, needle insertion, image-guidance, endpoint Assessment.- Thermal effects of irreversible electroporation.- Clinical practice: Irreversible electroporation of liver tumors .- Irreversible electroporation of pancreatic tumors.- Irreversible electroporation for perihilar cholangiocarcinoma (Klatskin tumors).- Irreversible electroporation of kidney tumors.- Irreversible Electroporation of Prostate Tumors.- Irreversible electroporation of tumors within the pelvic cavity.- Irreversible Electroporation of Lung Tumors.- Future prospectives: From local to systemic treatment: leveraging antitumor immunity following irreversible electroporation.- Future perspectives of IRE.
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